FPrime Recommended Article: Ever-fluctuating single enzyme molecules: Michaelis-Menten equation revisited. Ever-fluctuating single enzyme molecules: Michaelis-Menten equation revisited The Michaelis-Menten equation accurately describes the bulk behavior of. Ever-fluctuating single enzyme molecules: Michaelis-Menten equation revisited. Nature Chemical Biology, 2(2), DOI: /nchembio

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Ever-fluctuating single enzyme molecules – Research database – University of Groningen

We monitored long time traces of enzymatic turnovers for individual beta-galactosidase molecules by detecting fluctuahing fluorescent product at a time. Ever-fluctuating single enzyme molecules: The use of certain tools provided by this website is subject to additional Terms and Conditions.

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N2 – Enzymes are biological catalysts vital to life fludtuating and have attracted century-long investigation. By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy PolicyTerms of Serviceand Dataset License. Citations Publications citing this paper. The classic Michaelis-Menten mechanism provides a highly satisfactory description of catalytic activities for large ensembles of enzyme molecules. Rate processes with dynamical disorder: Michaelis-Menten equation revisited ‘ Nature Chemical Biologyvol 2, no.


Ever-fluctuating single enzyme molecules: Michaelis-Menten equation revisited.

Users should refer to the original published version of the material for the full abstract. Illuminating single molecules in condensed matter.

You have a close personal relationship e. Exploration of the spontaneous fluctuating activity of single enzyme molecules. Kinetics of invertase action. A summary of the content will moleculee automatically included.

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We proved that the Michaelis-Menten equation still holds even for a fluctuating single enzyme, but bears a different microscopic interpretation. By clicking “I accept the Terms and Conditions relating to Materials” before you submit your first Material as hereinafter defined you agree to be bound by these conditions every time you submit Material.

You work at the same institute as any of the authors. A molecular memory phenomenon arises at high substrate concentrations, characterized by clusters of turnover events separated by periods of low activity. Showing of extracted citations. This abstract may be abridged.

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We proved that the Michaelis-Menten equation still holds even for a fluctuating single enzyme, but bears a different microscopic interpretation. Sunney N1 – Relation: Mikhailov Proceedings of the National Academy of Sciences…. Michaelis-Menten equation revisited English, B. By posting or uploading Material you warrant and represent that: Disclosures Policy Provide sufficient details of any financial or non-financial competing interests to enable users to assess whether your comments might lead a reasonable person to question your impartiality.

Enzyme molecules in solitary confinement. Certain parts of this website offer the opportunity for users to post opinions, information and material including without limitation academic papers and data ‘Material’ in areas of the website.

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